Peroxisome biogenesis, protein targeting mechanisms and PEX gene functions in plants

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Peroxisome biogenesis, protein targeting mechanisms and PEX gene functions in plants.

Peroxisomes play diverse and important roles in plants. The functions of peroxisomes are dependent upon their steady state protein composition which in turn reflects the balance of formation and turnover of the organelle. Protein import and turnover of constituent peroxisomal proteins are controlled by the state of cell growth and environment. The evolutionary origin of the peroxisome and the r...

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Defective PEX gene products correlate with the protein import, biochemical abnormalities, and phenotypic heterogeneity in peroxisome biogenesis disorders.

Peroxisome biogenesis disorders (PBD) comprise three phenotypes including Zellweger syndrome (ZS) (the most severe), neonatal adrenoleucodystrophy, and infantile Refsum disease (IRD) (the most mild), and can be classified into at least 12 genetic complementation groups, which are not predictive of the phenotypes. Several pathogenic genes for PBD groups have been identified, but the relationship...

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Peroxisome Function, Biogenesis, and Dynamics in Plants.

1 1 Short title: Update on plant peroxisomes 2 3 Corresponding author: Bonnie Bartel, Rice University, MS-140, 6100 Main Street, 4 Houston, Texas 77005; Phone: 713-348-5602; E-mail: [email protected] 5 6 7 Peroxisome function, biogenesis, and dynamics in plants 8 9 Yun-Ting Kao2, Kim L. Gonzalez2, and Bonnie Bartel* 10 11 Department of Biosciences, Rice University, Houston Texas 77005 12 13 ORCID...

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Peroxisome assembly: matrix and membrane protein biogenesis

The biogenesis of peroxisomal matrix and membrane proteins is substantially different from the biogenesis of proteins of other subcellular compartments, such as mitochondria and chloroplasts, that are of endosymbiotic origin. Proteins are targeted to the peroxisome matrix through interactions between specific targeting sequences and receptor proteins, followed by protein translocation across th...

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The PEX 1 ATPase stabilizes PEX 6 and plays essential roles in peroxisome

Short title: 1 Plant PEX1 is essential for peroxisomes 2 3 Corresponding author: 4 Bonnie Bartel, Rice University, MS-140, 6100 Main Street, Houston, Texas 77005; Phone: 7135 348-5602; E-mail: [email protected] 6 7 8 9 The PEX1 ATPase stabilizes PEX6 and plays essential roles in peroxisome biology 1 10 11 Mauro A. Rinaldi 2 , Wendell A. Fleming, Kim L. Gonzalez, Jaeseok Park 3 , Meredith J. Ventu...

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ژورنال

عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

سال: 2016

ISSN: 0167-4889

DOI: 10.1016/j.bbamcr.2015.09.027